Fatty acid-binding protein 4
WebJun 26, 2024 · Serum fatty acid-binding protein 4 (FABP4), as an intracellular lipid chaperone and adipokine, was reported to be related to the incidence of type 2 diabetes (T2D) and diabetic complications, but its association with pancreatic islet β-cell and α-cell functions has not been fully elucidated. WebApr 8, 2024 · Childhood cancer survivors are highly exposed to the development of side effects after many years of cessation of anticancer treatment, including altered lipid …
Fatty acid-binding protein 4
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WebaP2 (adipocyte Protein 2) is a carrier protein for fatty acids that is primarily expressed in adipocytes and macrophages. aP2 is also called fatty acid binding protein 4 (FABP4). … Web3.4.4 Adipocyte-specific fatty acid-binding protein A-FABP is an important protein mainly expressed in mature adipocytes and macrophages and accounts for approximately 6% of total cellular protein [173].
WebFatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. WebJul 1, 2011 · Obese diabetic women and their fetuses had elevated serum triglyceride levels. Nonesterified fatty acids were elevated and triglycerides were reduced in placental villi from obese diabetic women, and this was accompanied by a 2.6-fold increase in FABP4 expression (P < 0.05).In primary human trophoblasts, fatty acids markedly increased the …
WebApr 6, 2009 · Fatty acid binding protein 4 (FABP4; adipocyte-FABP; aP2) is a member of the family of intracellular FABPs .The FABP family consists of 9 highly conserved cytosolic proteins that are abundantly expressed in a tissue-specific manner with some overlap .FABPs are capable of binding a variety of hydrophobic ligands, such as long-chain … WebIn 1972, fatty acid binding proteins (FABPs) were described for the first time (Ockner et al., 1972).These intracellular cytosolic proteins with relatively low molecular masses …
WebEpidermal fatty acid-binding protein (EFABP) is uniquely expressed in epidermal cells, but its role and expression in HCC are not clear. Subjects and methods: A total of 804 HCC specimens were collected to construct a tissue microarray (TMA) and for immunohistochemistry (IHC) analysis. The relationship between EFABP expression and …
WebThe fatty-acid-binding proteins (FABPs) are a family of transport proteins for fatty acids and other lipophilic substances such as eicosanoids and retinoids. These proteins … spider man 2 ps1 onlineWebMar 23, 2024 · The present study revealed impairment of lipid metabolism in papillae with calcified plaque tissue and down-regulation of fatty acid-binding protein 4 (FABP4) associated with plaque formation. Immunohistochemistry of human kidney specimens and experiments of nephrocalcinosis model mice and Fabp4 knockout mice validated FABP4 … spider man 2 ps2 isoWebFatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. [5] FABP7 is expressed, during development, in radial glia by the activation of Notch receptors. [6] spider-man 2 screenplayWebSep 15, 2024 · Fatty acid-binding protein 4 (FABP4) is a member of the fatty acid-binding protein family, which are a group of small proteins with a molecular weight of 14–15 kDa (Reese-Wagoner et al., 1999; Shi et al., 2024b). Human FABP4 is located on chromosome 8q21 and encodes a polypeptide of 132 amino acids (Smathers and … spider man 2 streamcloudWebApr 4, 2024 · Fatty acid-binding protein 4 is a therapeutic target for septic acute kidney injury by regulating inflammatory response and cell apoptosis. FABP4 activates the JAK2/STAT2 pathway via Rap1a in the homocysteine-induced macrophage inflammatory response in ApoE(-/-) mice atherosclerosis. spider-man 2 spider-man is a criminalWebMar 21, 2024 · FABP3 (Fatty Acid Binding Protein 3) is a Protein Coding gene. Diseases associated with FABP3 include Pulmonary Embolism and Acute Myocardial Infarction . Among its related pathways are Triglyceride metabolism and Metabolism . Gene Ontology (GO) annotations related to this gene include transporter activity and cytoskeletal … spider man 2 the game crakdWebThe adipocyte fatty acid binding protein (FABP4) binds a long chain fatty acid, providing solubility and proper cellular trafficking of fatty acids. Using FABP4 null animal models, we (and others) have shown a major protection from obesity-dependent diseases. spiderman 2 tobey maguire alamy